Polymorphous low-grade adenocarcinoma
| Polymorphous low-grade adenocarcinoma |
| Classification and external resources |
Low magnification micrograph of a polymorphous low-grade adenocarcinoma, showing the typical variation of architectural arrangement. H&E stain. |
Polymorphous low-grade adenocarcinoma, often abbreviated PLGA, is a rare, slow-growing malignant salivary gland tumor.[1] It is most commonly found in the palate.[2]
The name of the tumor derives from the fact that:
- It has a varied microscopic architectural appearance, i.e. it is polymorphous.
- It is non-aggressive when compared to other oral cavity tumors, i.e. it is a low-grade tumor.[1]
- It forms glands, i.e. it is an adenocarcinoma.
Histology
PLGAs consist of a monomorphous cell population that has a varied histologic morphology.
Microscopically, its histology can be confused with an adenoid cystic carcinoma and a pleomorphic adenoma.
Treatment
PLGAs are treated with wide local surgical excision and long-term follow-up.[2]
Additional images
Additional reading
- Kahn, Michael A. Basic Oral and Maxillofacial Pathology. Volume 1. 2001.
References
- ^ a b Arathi N, Bage AM (2009). "Polymorphous low-grade adenocarcinoma of parotid gland: a rare occurrence". Indian J Pathol Microbiol 52 (1): 103–5. PMID 19136798.
- ^ a b Paleri V, Robinson M, Bradley P (April 2008). "Polymorphous low-grade adenocarcinoma of the head and neck". Curr Opin Otolaryngol Head Neck Surg 16 (2): 163–9. doi:10.1097/MOO.0b013e3282f70441. PMID 18327037.
External links